Menopause is the natural biological stage marking the failure of the ovaries to produce female hormones and is defined by the permanent cessation of menstrual periods. It is diagnosed retrospectively after twelve consecutive months without menstruation, without any other underlying medical cause. This transition reflects a significant decline in ovarian function, particularly a reduction in the production of the hormones oestrogen and progesterone, which are essential for regulating the menstrual cycle and supporting fertility.
Menopause typically occurs between the ages of 45 and 55, with the average age in Singapore being 49. However, the timing can vary due to factors such as genetics, overall health, smoking, certain medical treatments or surgical removal of the ovaries (surgical menopause). While it is a normal part of ageing, menopause is often preceded by perimenopause, a transitional phase characterised by hormonal fluctuations and changes in menstrual patterns and followed by postmenopause, the years after menstruation has ceased.
Although menopause is not an illness, the hormonal changes associated with it can lead to a range of physical and emotional symptoms, including hot flushes, night sweats, sleep disturbances, mood changes and vaginal dryness/ sexual dysfunction. Understanding menopause as a natural life stage, rather than a disease, is essential for providing appropriate support, lifestyle guidance, and, where necessary, medical management to help women maintain health and quality of life during and after this transition.
Menopause is not a single event but a gradual process that unfolds over several years, typically progressing through three distinct stages: perimenopause, menopause and postmenopause. Each stage involves characteristic hormonal changes, symptoms and implications for health.
Menopause occurs because of a natural decline in ovarian function due to the loss of all viable eggs, leading to reduced production of the sex hormones, oestrogen and progesterone. These hormones regulate the menstrual cycle and support reproductive health. Prior to this, as a woman ages, the number and quality of eggs in the ovaries diminish, and in peri-menopause ovulation (the release of eggs) becomes less frequent or irregular. Eventually, ovulation stops altogether, menstrual periods cease and menopause ensues.
While menopause is a normal part of ageing, certain factors can cause it to occur earlier than usual or bring it on suddenly:
The signs of menopause arise from declining oestrogen and progesterone levels and can vary widely in nature, severity and duration from one woman to another. Some women experience only mild changes, while others notice symptoms that affect their quality of life. These signs may begin during perimenopause and continue into postmenopause.
Common signs include:
These signs can be temporary or persist for several years. Recognising them early allows women to seek appropriate support and management to maintain comfort and quality of life during the menopause transition.
Premature menopause refers to the onset of menopause before the age of 40. Like natural menopause, it involves the permanent end of menstrual periods due to a significant drop in ovarian hormone production, but it occurs much earlier than expected. This can happen naturally, when the ovaries stop functioning well before midlife or it can be triggered by medical interventions such as surgical removal of the ovaries, chemotherapy or radiotherapy.
When premature menopause occurs without a clear medical cause, it is often diagnosed as primary ovarian insufficiency (POI). In POI, the ovaries lose their normal function years earlier than typical, which may be linked to genetic factors, autoimmune disease, or, in many cases, no identifiable reason at all.
The early loss of oestrogen has health implications beyond fertility. Women who go through premature menopause face an increased risk of osteoporosis, cardiovascular disease, and certain mood disorders, and they may also experience more intense menopausal symptoms. Because of these risks, timely diagnosis and tailored management, often including hormone replacement therapy (HRT) unless contraindicated, are important to protect long-term health and quality of life.
The duration of menopause symptoms varies widely between individuals. For many women, symptoms such as hot flushes, night sweats and mood changes begin during perimenopause and continue for several years after the final menstrual period. On average, these symptoms last about four to five years, but in some cases they can persist for a decade or more.
Hot flushes and night sweats tend to be most frequent and intense in the early postmenopausal years, gradually reducing over time. Other symptoms, such as vaginal dryness and discomfort during intercourse, may become more noticeable later and can continue indefinitely without treatment, due to persistently low oestrogen levels.
Certain factors can influence how long symptoms last and how severe they feel, such as:
Managing symptoms early, whether through lifestyle measures, hormone therapy or other treatments, can help improve comfort and quality of life throughout the menopause transition.
Diagnosis is based mainly on symptoms and menstrual history, rather than a single definitive test, though hormone testing gives further evidence to what is occuring. The most reliable sign is having no menstrual periods for twelve consecutive months without another underlying medical cause.
Ways menopause may be diagnosed include:
This structured approach ensures that menopause is accurately identified and managed appropriately, especially when symptoms occur earlier than expected or overlap with other conditions.
The drop in oestrogen levels after menopause affects more than just reproductive function. It also influences bone density, heart health and other body systems, increasing the risk of certain long-term conditions. Understanding these risks allows women to take preventive steps early.
Key health risks include:
These risks highlight the importance of regular health checks, healthy lifestyle habits and timely medical advice to protect long-term well-being after menopause.
While menopause is a natural stage of life, medical advice is important if symptoms are severe, disruptive or occur earlier than expected. Seeking professional help ensures that other health conditions are not overlooked and that you receive the right management for your needs.
It is advisable to see a doctor if you experience:
Early medical input can help tailor treatment options, monitor health risks and improve quality of life during and after menopause.
Managing menopause includes relieving symptoms, improving quality of life and reducing long-term health risks associated with low oestrogen levels. The right approach depends on the type and severity of symptoms, personal health history and individual preferences.
Common options include:
Treatment should always be individualised, with regular reviews to ensure it remains safe and effective over time.
Adopting healthy daily habits can ease the severity of menopausal symptoms, improve mood and energy levels and support long-term health after menopause. While lifestyle changes may not eliminate symptoms entirely, they often complement medical treatments and provide additional benefits.
Helpful lifestyle adjustments include:
These lifestyle measures can be tailored to individual needs and, when maintained consistently, help women feel more in control during the menopause transition.
HRT, which involves replacing declining levels of oestrogen and sometimes progesterone, can be an effective way to relieve menopause symptoms and protect bone health. However, it is not suitable for everyone.
Women with a history of breast cancer, certain types of gynaecological cancer, unexplained vaginal bleeding, blood clots, liver disease or uncontrolled high blood pressure may be advised to avoid HRT. Suitability depends on individual health history, current medical conditions, and personal risk factors, which is why a thorough medical assessment is essential before starting treatment.
The side effects of HRT can vary depending on the type, dose and method of delivery, as well as how an individual’s body responds. Some effects are temporary and improve as the body adjusts, while others may require a change in treatment or closer monitoring.
Possible side effects include:
Regular reviews with a healthcare professional help ensure that benefits outweigh risks and that any side effects are addressed promptly.
Menopause is a natural stage in a woman’s life marked by the permanent end of menstrual periods, usually occurring between the ages of 45 and 55. It progresses through perimenopause, menopause, and postmenopause, with symptoms ranging from hot flushes, night sweats and mood changes to vaginal dryness and changes in bone and heart health.
While it is most often caused by the natural decline in ovarian function, factors such as surgery, certain medical treatments or primary ovarian insufficiency can lead to earlier onset. Diagnosis is based on symptoms and menstrual history, and management options include hormone replacement therapy (HRT), non-hormonal medicines, lifestyle adjustments, and bone health support. Understanding the potential health risks, including osteoporosis, cardiovascular disease, and mood disorders, and seeking timely medical advice ensures better long-term well-being.
If you are experiencing symptoms of menopause or want guidance on managing this transition, schedule a consultation with us for a detailed diagnosis and personalised treatment plan.
Fluctuating oestrogen levels affect the brain’s temperature control centre, causing sudden heat surges, sweating and sometimes palpitations.
Hot flushes, night sweats, irregular periods, mood changes, vaginal dryness, sleep disturbances and changes in skin or hair are among the most common symptoms of menopause.
Yes. Hormonal changes, combined with sleep disruption, can lead to memory lapses, difficulty concentrating and emotional fluctuations.
Reduced oestrogen after menopause accelerates bone loss, increasing the likelihood of osteoporosis and fractures.
Lower oestrogen can contribute to unfavourable cholesterol changes, increased abdominal fat, and higher risks of heart disease and type 2 diabetes.
Yes. A slower metabolism and hormonal changes often shift fat distribution towards the abdomen, even without major changes in diet.
Skin may become drier and less elastic, hair can thin and some women experience joint stiffness or discomfort due to hormonal decline.
Lower oestrogen can cause vaginal dryness, reduced elasticity and discomfort during intercourse, which may affect sexual desire.
Mammograms, cervical screening, bone density scans and cardiovascular risk assessments remain important to monitor long-term health.
Yes. Certain antidepressants, blood pressure medicines and vaginal moisturisers can help, alongside lifestyle and dietary adjustments.
Regular exercise, a balanced diet, stress reduction, good sleep habits and avoiding symptom triggers can help reduce severity and improve well-being.
Yes. Hot flushes, night sweats and mood changes can disturb sleep, leading to daytime fatigue and reduced energy.
Managing sleep quality, reducing stress, staying physically active and engaging in mentally stimulating activities can help maintain cognitive function.
Some, such as hot flushes or vaginal dryness, may continue for years after menopause, though frequency and intensity often decrease over time.
MBBS (Hons), FRACP (Australia)
Dr Dinesh graduated with honours from Monash University, Melbourne in 2009, receiving the Prince Henry's Prize in Surgery. During his endocrinology training in Melbourne, he won the top registrar award at the Endocrine Society of Australia Clinical Weekend in 2016, followed by securing Australia's only Andrology fellowship in 2017. Upon returning to Singapore, he was the sub-speciality lead for adrenal, pituitary, and bone services at Khoo Teck Puat Hospital and established The Metabolic Bone Clinic.
A passionate educator, he served as Associate Programme Director for Endocrinology at NHG, training the next generation of endocrinologists, and received the NHG Teaching Award for Senior Doctors in 2023. An expert endocrinologist with proficiency in both general and sub-speciality endocrinology, he has an interest in longevity through improving cardiovascular risk, metabolism, bone health, and muscle loss prevention, with the ultimate aim of improving the number of healthy years in one's life.
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